Epidermolysis bullosa simplex

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Epidermolysis bullosa simplex (EBS),is a disorder resulting from mutations in the genes encoding keratin 5 or keratin 14.

Blister formation of EBS occurs at the dermoepidermal junction. Sometimes EBS is called epidermolytic.

Video Epidermolysis bullosa simplex

Cause

Maps Epidermolysis bullosa simplex

Diagnosis

Classification

Epidermolysis bullosa simplex may be divided into multiple types:

src: escholarship.org

Management

• no cure for EB
• treat symptomatic
• protect skin, stop blisters formation, promote healing
• prevents complications
• Necessary treatment: use oral & topical steroid for healing & prevent complication
• maintain cool environment, avoid overheating & decreases friction

src: escholarship.org

See also

• Epidermolysis bullosa
• List of cutaneous conditions caused by mutations in keratins

src: www.jbc.org

References

src: healthjade.com

Further reading

• GeneReviews/NCBI/UW/NIH entry on Epidermolysis Bullosa Simplex

src: medcell.med.yale.edu

External links

Source of article : Wikipedia